ABSTRACT
Botanical extracts [8%] of four plants [Artemisia monosperma, Zygophyllum cocccineum, Lupinus termis and Brassica tournifortii] fed to the 4[th] larval in-stars of Spodoptera littoralis induced histopathological changes in the structure of the midgut, integument and fat body of the 5[th] instars. Zygophyllum coccineum and Lupinus termis induced severe damages in the midgut. The integument of treated larvae showed degeneration in the cuticle and epidermal cells which were also detached from each other. Water extracts of A. monosperma, Z. coccinieum and L. termis were the most promising in inducing shrinkage in the fat body cells and detachment of midgut muscle layers. Also, the degeneration of the midgut membrane and epithelial layer occurs in different degrees with the tested plants. This study supports the use of botanical extracts in pest control programs of lepidopterous insects